R.G.C.C. | R.G.C.C. Published Articles

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Anticancer Drugs Journal.



The use of serum extracellular vesicles for novel small molecule inhibitor cell delivery.

Authors: Hatzidaki E, Vlachou I, Elka A, Georgiou E, Papadimitriou M, Iliopoulos A, Papasotiriou I.


ESMO AnnualConference, 2018



Risk prediction of metastasis through study of circulating tumor cells.

Authors: Apostolou P., Papasotiriou I.


DGHO - JAHRESTAGUNG 2018, Vienna



Retrotransposons in circulating free DNA from cancer patients.

Authors: Apostolou P., Parsonidis P., Papasotiriou I.


European Society for Clinical Cell Analysis, Valencia, 2018



CD163 detection in breast cancer patients' peripheral blood. A possible marker?

Authors: Ntanovasilis D.A., Papasotiriou I.


European Magnetic Resonance Meeting (EUROMAR) 2018, Nantes



Quantitative Nuclear Magnetic Resonance for the determination of Genistein in capsules.

Authors: Vlachou I, Papasotiriou I.


ASCO Annual Meeting 2018



CTCs enumeration and profile in different cancer types in a group of patients from United States.

Authors: Ioannis Papasotiriou, Dimitrios Ntanovasilis, Panagiotis Apostolou


ESMO GI 2018, Barcelona



Molecular profiling of gastrointestinal cancer.

Authors: Apostolou P, Papadimitriou M, Parsonidis P, Iliopoulos A.C, Papasotiriou I.


Cambridge Healthtech Institute, Molecular diagnostics Europe, Lisbon



Isolation and characterization of CTCs from breast cancer patients with and without metastasis

Authors: Ntanovasilis D.A, Apostolou P, Papadimitriou M. Papasotiriou I.


International Society of Extracellular Vesicles, Barcelona, 2018



EV-encapsulated small molecule inhibitor decreases viability in cancer cell lines.

Authors: Eleana Hatzidaki, Ioanna Vlachou, Maria Papadimitriou, Ioannis Papasotiriou


Isac cyto 2018, Prague



Flow cytometric analysis of CTCs in breast cancer patients before and after chemotherapy

Authors: Ntanovasilis D.A., Papasotiriou I.


AACR-Targeting DNA Methylation and Chromatin for Cancer Therapy



CTCs contribution in cancer therapy and progression.

Authors: Yamaguchi N.H., Barreto C.M.N., Oliveira P.B.T., Manfrinato M.F.G., Silvério F.S., Spada M.T.A., Santos A.S., da Silva A.Q.C., Yasksic M.S., Ntanovasilis D., Apostolou P., Papasotiriou I.,


Journal of Biological Research-Thessaloniki



Evaluation of a simple method for storage of blood samples that enables isolation of circulating tumor cells 96 h after sample collection.

Authors: Panagiotis Apostolou, Dimitrios-Athanasios Ntanovasilis and Ioannis Papasotiriou


Archives of Clinical Microbiology



Detection and identification of bacterial contamination in blood samples from cancer patients.

Authors: Katerina Pantopikou, Ioannis Papasotiriou


Breast Cancer: Targets and Therapy



Current perspectives on CHEK2 mutations in breast cancer.

Authors: Panagiotis Apostolou, Ioannis Papasotiriou


Journal of Cancer Therapy



Stemness Gene Profiles of Circulating Tumor Cells.

Authors: Panagiotis Apostolou, Maria Papadimitriou, Ioannis Papasotiriou


PLoS One



L1 retrotransposon expression in circulating tumor cells.

Authors: Ioannis Papasotiriou, Katerina Pantopikou and Panagiotis Apostolou

DGHO JAHRESSTAGUNG 2017



Comparative study of L1 between lung cancer and healthy samples.

Authors: Pantopikou K. Apostolou P. Papasotiriou I.

ESMO World Congress on Gastrointestinal Cancer 2017



The molecular profile of colon cancer cells.

Authors: Apostolou P., Ntanovasilis D., Papadimitriou M., Hatzidaki E., Pantopikou K., Parsonidis P., Papasotiriou I.

ASCO Annual Meeting 2017



Comparison of genomic and gene expression profile between cancer and healthy samples.

Authors: Ioannis Papasotiriou, Dimitrios Ntanovasilis, Panagiotis Apostolou


ANTICANCER RESEARCH International Journal of Cancer Research and Treatment



Generation of Human Antibodies Against a Specific Peptide: a Novel Strategy Based on Human Cells.

Authors: Maria Toloudi, Maria Papadimitriou, Katerina Pantopikou And Ioannis Papasotiriou


Molbank Journal MDPI



9-(4-Methoxyquinazolin-2-yl)-9H-purin-6-amine.

Authors: Ioanna Vlachou, Eleni Kourtidou and Ioannis Papasotiriou

EORTC-NCI-AACR Molecular Targets and Cancer Therapeutics Symposium, Munich - Germany



The study of L1 in prostate cancer.

Authors: Pantopikou Katerina, Apostolou Panagiotis, Papasotiriou Ioannis

Jahrestagung 2016, Leipzig



The role of L1 retrotransposon in circulating tumor cells.

Authors: Panagiotis Apostolou, Ioannis Papasotiriou

18th WORLD CONGRESS ON Gastrointestinal Cancer 2016, Barcelona



The genetic profile of pancreatic circulating tumor cells.

Authors: Panagiotis Apostolou, Maria Toloudi, Maria Papadimitriou and Ioannis Papasotiriou

ASCO Annual Meeting 2016



Studying the gene expression profile among circulating tumor cells.

Authors: Ioannis Papasotiriou, Dimitrios Ntanovasilis, Panagiotis Apostolou.

Journal of Cancer Therapy



DC Maturation A Brief Comparison between Three Different Processes.

Authors: Maria Toloudi and Ioannis Papasotiriou


Journal of Cancer Therapy



Gene Expression Changes in Colorectal Cancer during Metronomic Chemotherapy and High-Concentration Drug Administration

Authors: Panagiotis Apostolou, Maria Toloudi, Irene Kalliara, Vasiliki Kipourou, Ioanna Tourna and Ioannis Papasotiriou

Breast Cancer: Targets and Therapy



Identification of genes involved in breast cancer and breast cancer stem cells

Authors: Panagiotis Apostolou, Maria Toloudi, Ioannis Papasotiriou


Journal of Cancer Therapy



Detection of Circulating Tumor Cells in Patients with Breast, Prostate, Pancreatic, Colon and Melanoma Cancer: A Blinded Comparative Study Using Healthy Donors

Authors:Ioannis Papasotiriou, Marina Chatziioannou, Konstantina Pessiou, Ippokratis Retsas, Georgia Dafouli, Antigoni Kyriazopoulou, Maria Toloudi, Irene Kaliara, Ioanna Vlachou, Eleni Kourtidou, Vasiliki Kipourou, Evanthia Georgiou, Dimitrios Athana

Endocrinology, Diabetes & Metabolism CASE REPORTS



Tumor-induced osteomalacia due to a recurrent mesenchymal tumor overexpressing several growth factor receptors.

Authors : Maria P Yavropoulou, Nikolina Gerothanasi, Athanasios Frydas, Evangelia Triantafyllou, Chris Poulios, Prodromos Hytiroglou, Panagiotis Apostolou, Ioannis Papasotiriou, Symeon Tournis, Isaak Kesisoglou and John G Yovos

Journal of Cancer Therapy



Efficacy of 5-FU or Oxaliplatin Monotherapy over Combination Therapy in Colorectal Cancer.

Authors : Maria Toloudi, Panagiotis Apostolou and Ioannis Papasotiriou

Jahrestagung 2015, Basel



The metastatic profile of breast cancer stem cells and circulating tumor cells.

Authors: Apostolou P., Toloudi M., Kalliara I., Papasotiriou I.

Dr Abe’s Conference in Osaka, Japan.



Circulating Tumor Cells: Challenges in Detection and Isolation.

Author-Presenter: Dr. Ioannis Papasotiriou

Involvement of retrotransposon L1 in stemness and cellular plasticity



ABSTRACT

Authors: Panagiotis Apostolou, Maria Toloudi, Marina Chatziioannou, Eleni Kourtidou, Georgia Mimikakou, Ioanna Vlachou, Aikaterini Chlichlia and Ioannis Papasotiriou


PLoS ONE



Potential Role for the Metnase Transposase Fusion Gene in Colon Cancer through the Regulation of Key Genes

Authors: Panagiotis Apostolou, Maria Toloudi, Eleni Kourtidou, Georgia Mimikakou, Ioanna Vlachou, Marina Chatziioannou, Vasiliki Kipourou, Ioannis Papasotiriou


Journal of Biological Research-Thessaloniki



Use of the comet assay technique for quick and reliable prediction of in vitro response to chemotherapeutics in breast and colon cancer

Authors: Panagiotis Apostolou, Maria Toloudi, Eleni Kourtidou, Georgia Mimikakou, Ioanna Vlachou, Marina Chatziioannou and Ioannis Papasotiriou

J CRT - Journal of Cancer Research and therapeutics



How prostate-specific membrane antigen level may be correlated with stemness in prostate cancer stem cell-like cell populations?

Authors: Maria Toloudi, Panagiotis Apostolou, Marina Chatziioannou, Eleni Kourtidou, Ioanna Vlachou, Georgia Mimikakou, Ioannis Papasotiriou

2 014 ASCO Annual Meeting



TMX2: A potential biomarker or a predictive marker in breast cancer?

Authors: Ioannis Papasotiriou, Panagiotis Apostolou, Maria Toloudi, Marina Chatziioannou, Georgia Mimikakou, Eleni Kourtidou, Ioanna Vlachou.

C urrent Stem Cell Research & Therapy



Comparison of the growth curves of cancer cells and cancer stem cells.

Authors: Toloudi M, Ioannou E, Chatziioannou M, Apostolou P, Kiritsis C, Manta S, Komiotis D, Papasotiriou I.

Jahrestagung 2014, Hamburg



The study of Tmx2 in self-renewal and pluripotency in breast cancer.

Authors: Apostolou P., Toloudi M., Chatziioannou M., Mimikakou G., Kourtidou E., Vlachou I., Kipourou V., Papasotiriou I.

ESMO GI 2014 Barcelona



The genetic background of pancreatic cancer: Genes that might be biomarkers or indicators of metastasis to the lung.

Authors: Apostolou P., Toloudi M., Kourtidou E., Vlachou I., Mimikakou G., Chatziioannou M., Papasotiriou I.

Magazine of European Medical Oncology-MEMO



Targeted delivery of anticancer agents using antibodies as vectors

Authors: Maria Toloudi MD, Ioannis Papasotiriou MD, PhD

M agazine of European Medical Oncology-MEMO



The contribution of antibodies to targeted cancer therapy

Authors: Panagiotis Apostolou, Dr. Ioannis Papasotiriou

J ournal of Signal Transduction, Volume 2013, ID 497383



AP-1 Gene Expression Levels May Be Correlated with Changes in Gene Expression of Some Stemness Factors in Colon Carcinomas

Authors: Panagiotis Apostolou, Maria Toloudi, Eleni Ioannou, Marina Chatziioannou, Eleni Kourtidou, Ioanna Vlachou, and Ioannis Papasotiriou

J ournal of Receptors and Signal Transduction



Study of the interaction among Notch pathway receptors, correlation with stemness, as well as their interaction with CD44, dipeptidyl peptidase-IV, hepatocyte growth factor receptor and the SETMAR transferase, in colon cancer stem cells.

Authors: Apostolou P, Toloudi M, Ioannou E, Kourtidou E, Chatziioannou M, Kopic A, Komiotis D, Kiritsis C, Manta S, Papasotiriou I.

B MC Pharmacology and Toxicology 2013, 14:18



Anvirzel™ in combination with cisplatin in breast, colon, lung, prostate, melanoma and pancreatic cancer cell lines.

Authors: Apostolou P, Toloudi M, Chatziioannou M, Ioannou E, Knocke DR, Nester J, Komiotis D, Papasotiriou I.

Jahrestagung 2013 , Vienna



The MAPK/ERK pathway among Colon Cancer Cells, Colon Cancer Stem Cells, Embryonic Stem Cells and Normal Cells.

Authors: Apostolou P., Toloudi M., Chatziioannou M., Ioannou E., Kourtidou E., Vlachou I., Papasotiriou I.

The study of GSTP1 Ile105Val polymorphism among normal, cancer and cancer stem cells, in a wide spectrum of human tumors

Authors: Apostolou P., Toloudi M., Chatziioannou M., Ioannou E., Kourtidou E., Vlachou I., Papasotiriou I.

1 5th World Congress of Gastrointestinal Cancer , Barcelona



The study of gene expression as a tool for predicting response to chemotherapy in pancreatic cancer.

Authors: Apostolou P., Toloudi M., Chatziioannou M., Ioannou E., Papasotiriou I.

1 9th Conference of Clinical Oncology Athens



Is there any Correlation between the number change in circulating tumor cells and the clinical evaluation in cancer patients?

Authors: Chatziioannou M.1, Kyriazopouloy A. 1, Ioannou Ε.1, Toloudi Μ.1, Apostolou P.1, Hammon R.2, Hembry N.4, Jacob U.3, Kopic A.3, Papasotiriou Ι

S cience to Market 2013. Personalised Medicine - Trends in 2013. – Cologne, Germany



DCs as cancer vaccines. Mature DCs as a tool to sustain minimal residual disease status in malignancies.

Authors: E. Ioannou, M. Chatziioannou, M. Toloudi, P. Apostolou, I. Papasotiriou

24th EORTC NCI AACR Symposium – Dublin



DCs as cancer vaccines. Mature DCs as a tool to sustain minimal residual disease status in malignancies.

Authors: E. Ioannou, M. Chatziioannou, M. Toloudi, P. Apostolou, I. Papasotiriou

C urrent Stem Cell Research & Therapy, 2012, 7, Pp 415-419



Cancer Stem Cells Stemness Transcription Factors Expression Correlates with Breast Cancer Disease Stage

Authors:Panagiotis Apostolou, Maria Toloudi, Marina Chatziioannou, Eleni Ioannou and Ioannis Papasotiriou

B reast Cancer, Locally advanced and metastatic.



Cancer Stem Cell-Like cells: A Therapeutic model in breast cancer patients, where any other recommended therapy has failed.

Authors:I. Papasotiriou, M. Chatziioannou, M. Toloudi, E. Ioannou, R. Hammon, U. Jacob, N. Hembry, A. Kopic

S PR In correlation with ELISA



Development of a Sensitive Cost-Effective Capture ELISA for Detection of Murine Monoclonal Antibodies – Correlation with SPR Biosensor Technology

Authors:M. Tsiamita, M. Pavlaki, M. Toloudi, A. Tiptiri-Kourpeti, V. Drossou, P. Apostolou, M. Chatziioannou, E. Ioannou, I. Papasotiriou and K. Chlichlia

M edicinal Chemistry



Volume 8, Issue 6, Synthesis and Biological Evaluation of 3!-C-Ethynyl and 3!-C-(1,4- disubstituted-1,2,3-triazolo) Double-Headed Pyranonucleosides

Authors: Christos Kiritsis, Stella Manta, Ioannis Papasotiriou, Evdoxia Coutouli-Argyropoulou, Sakellarios Trakossas, Jan Balzarini and Dimitri Komiotis

N ucleosides, Nucleotides and Nucleic Acids, Taylor and Francis Group, LLC



Volume 31,Issue 7 – Stereocontrolled facile synthesis and biological evaluation of (3_S) and (3_R)-3 – Amino (and Azido) -3 – Deoxy Pyranonucleosides.

Authors:Stella Manta, Vanessa Parmenopoulou, Christos Kiritsis, Athina Dimopoulou, Nikolaos Kollatos, Ioannis Papasotiriou, Jan Balzarini, and Dimitri Komioti

J ournal for Clinical Studies



JCS Volume 4, issue 1 – Effectiveness of CDDP and CV247 Combination, in Colon and Breast Carcinomas

2 4th EORTC NCI AACR Symposium – Dublin



Comparative study of Nanog, Oct3/4 and Sox2 gene expression following c-Met gene knockdown in Colon Cancer Stem Cells.

Chatziioannou M., Apostolou P., Toloudi M., Ioannou E., Hammon R., Hembry N.4, Kopic A., Komiotis D., Chlichlia K. ,Papasotiriou I.

J ahrestagung 2012, Stuttgart



Circulating Tumor Cells (CTCs) as a biomarker of relapse and metastasis: A review of 21 patients with breast cancer.

Authors: Chatziioannou M., Apostolou P., Toloudi M., Ioannou E., Retsas I. , R. Hammon, N. Hembry, U. Jacob, A. Kopic, Papasotiriou I.

Determination of the cytotoxicity of potential medical substances by using three colorimetric assays for mammalian cells.

Authors: M. Toloudi, P. Apostolou, M. Chatziioannou, E. Ioannou, I. Retsas, I. Papasotiriou

Studying the 5382insC polymorphism, of BRCA1 gene, in breast cancer and breast cancer stem cell-like cells.

Authors: P. Apostolou, M. Toloudi , M. Chatziioannou , E. Ioannou, I Retsas, I. Papasotiriou

A SCO-NCI-EORTC Annual Meeting on Molecular Markers in Cancer



Gene expression analysis of Notch signaling pathway receptors in Colon Cancer Stem Cells.

Authors:P. Apostolou, M. Toloudi , M. Chatziioannou , E. Ioannou, I. Papasotiriou

B reast Cancer, Locally advanced and metastatic.



Cancer Stem Cell-Like cells: A Therapeutic model in breast cancer patients, where any other recommended therapy has failed.

Authors: I. Papasotiriou, M. Chatziioannou, M. Toloudi, E. Ioannou, R. Hammon, U. Jacob, N. Hembry, A. Kopic

E SMO GI, Barcelona Spain



Correlation between FOLFOX regimen and stemness in colon CSCs

Authors: M. Toloudi, P. Apostolou, M. Chatziioannou, E. Ioannou, A. Kopic, I. Papasotiriou

1 8th Conference of Clinical Oncology Athens



Correlation of Number of circulating tumor cells and clinical development in patients with breast cancer of several stages.

Authors: M. Chatziioannou1 , M. Toloudi 1 , P. Apostolou 1 , E. Ioannou 1 , R. Hammon2, N. Hembry4, U. Jacob3, A. Kopic3, I. Papasotiriou

Correlation of Number of circulating tumor cells, chemotherapy and clinical development in breast cancer patients.

Author: M. Chatziioannou , M. Toloudi , P. Apostolou , E. Ioannou , R. Hammon, N. Hembry, U. Jacob, A. Kopic, I. Papasotiriou

Evaluation of clinical development of two patients with urinary bladder cancer before and after chemotherapy

Author: M. Chatziioannou, M. Toloudi, P. Apostolou, E. Ioannou, R. Hammon, N. Hembry, U. Jacob, A. Kopic, I. Papasotiriou

Studying the effect of stemness factors involved in molecular cascades of the development of colon cancer stem cells.

Authors:M. Toloudi, P. Apostolou, M. Chatziioannou, E. Ioannou, I. Papasotiriou

Studying the interaction of four receptors of NOTCH signaling pathway in breast cancer.

Author: P. Apostolou, M. Toloudi, M. Chatziioannou, E. Ioannou, I. Papasotiriou

Colon Cancer Cells and Cancer Stem Cells: A growth curves comparison.

Authors: E. Ioannou, M. Chatziioannou, M. Toloudi, P. Apostolou, I. Papasotiriou

Can Cancer stem cell – Like cells determine a therapeutic model in breast cancer patients when any other recommended therapy failed in this group? Considerations and single cases.

Authors:I. Papasotiriou, M. Chatziioannou, M. Toloudi, P. Apostolou, E. Ioannou, R. Hammon, N. Hembry, U. Jacob, A. Kopic

J ournal of Cardiothoracic Surgery



Bacterial and fungal microflora in surgically removed lung cancer samples.

Authors: Apostolou P., Tsantsaridou A., Papasotiriou I., Toloudi M., Chatziioannou M., Giamouzis G

J ournal for Clinical Studies



JCS Volume 3, Issue 5 - Studying the Effect Of Anvirzel, Carboplatin and Docetaxel Combination in NSCLC Cell Lines

I PI International Pharmaceutical Industry



IPI Volume 3, Issue 3 - Determination of Efficacy of Anvirzel™ in 37 Established Cancer Cell Lines

Journal for Clinical Studies



JCS Volume 3, Issue 4 -Predictive Value of Molecular-Cellular Methodologies for Response to Chemotherapy with CisPlatin/5Fu in Colon Tumours

IPI International Pharmaceutical Industry



IPI Volume 3, Issue 2 - RGCC: A Leading Company in Analysis of CSCs as Progenitors of All Cancer Relapses

J ournal for Clinical Studies



JCS Volume 3, Issue 3 - The Impact of CV247 Component on Human Cancer Cell Lines

C ase Report in Oncology



Case Report in Oncology - Brochure

Authors: Maria Toloudi, Panagiotis Apostolou, Marina Chatziioannou, Ioannis Papasotiriou

Correlation between Cancer Stem Cells and Circulating Tumor Cells and Their Value - Online Published

Authors: Maria Toloudi, Panagiotis Apostolou, Marina Chatziioannou, Ioannis Papasotiriou

6 2nd Hellenic conference of Biochemistry & Molecular BiologyAthens , Greece



Studying the impact of 5-FU in colon cancer cells in comparison with colon cancer stem cells.

Authors: E. Ioannou , P. Apostolou, M. Toloudi, M. Chatziioannou, I. Papasotiriou

6 th Annual Congress of the German Society for Stem Cell Research , Düsseldorf, Germany



Studying changes in gene expression of breast cancer stem cell-like cells markers, at different stages.

Authors: P. Apostolou, M. Toloudi, M. Chatziioannou, E. Ioannou, I. Papasotiriou

1 6th Conference of Oncology , Athens



Colon Cancer Stem Cell Study proves their resistance to Hypoxia

Authors: Chatziioannou M., Apostolou P., Toloudi M., Ioannou E., Papasotiriou I.

E ORTC-NCI-ASCO Annual Meeting on “Molecular Markers in Cancer” , Belgium'



Correlation between cancer stem cell-like cells markers and clinical assessment in breast cancer patients

Authors: Apostolou P., Toloudi M., Chatziioannou M., Papasotiriou I.

Studying the impact of nanog and other transcription factors in stemness pathway

J AHRESTAGUNG 2011 , BASEL



Adjustment of a cellular based methodology to predict response of doxorubicin in breast cancer

Authors: Apostolou P., Toloudi M., Chatziioannou M., Papasotiriou I.

Studying the level of PSMA expression in prostate cancer

Authors: Toloudi M., Apostolou P., Chatziioannou M., Papasotiriou I.

Comparison of Hypoxia Inducible Factor 1? _(HIF-1?_) levels in HCT-15 cell line and Human Colon Cancer Stem Cell-like Cells.

Authors: Chatziioannou M., Toloudi M., Apostolou P., Papasotiriou I.

E SMO Annual , Stockholm



Circulating tumor cells from peripheral blood as a prognostic marker for the clinical

Authors: Toloudi M., Apostolou P., Chatziioannou M., Papasotiriou I.

E SMO GI , Barcelona - Spain



Pancreatic CSC-like cells a new entity of CTCs

Authors: Toloudi M., Apostolou P., Chatziioannou M., Papasotiriou I.

1 7th World Congress on Menopause , Roma



Estrogen Promote Angiogenesis and Metastasis in Breast Cancer

Authors: Chatziioannou M., Apostolou P., Toloudi M., Papasotiriou I.

3 3rd Scientific Conference of Hellenic Society for Biological Science , Edessa



Adjustment of a Cellular Based Methodology to Predict Response to Melphalan - Oxaliplatin in Breast and Colon Cancer.

Authors: Apostolou P., Toloudi M., Chatziioannou M., Papasotiriou I.

1 7th Conference of Clinical Oncology Athens



Early Diagnoses of the Limited Number of Circulating Tumor Cells Significantly Increases the Early and Effective Treatment of the Disease.

Authors: Chatziioannou M., Apostolou P., Toloudi M., R. Hammon, U. Jacob, Papasotiriou I.

Studying the Effect of CV247 Component in Human Established Cancer Cell Lines Becoming From Prostate and Breast Carcinomas.

Authors: Apostolou P., Toloudi M., Chatziioannou M., Papasotiriou I.

Study of an extract of Nerium oleander, Anvirzel TM , in prostate and breast cancer cell lines.

Authors: Apostolou P., Toloudi M., Chatziioannou M., Papasotiriou I.